Twitch :: Wild Rift best builds and runes (Patch 4.4a)

Check out the best builds, items, and runes to play Twitch in Wild Rift, and get to know their abilities and combos!

A Zaunite plague rat by birth, but a connoisseur of filth by passion, Twitch is not afraid to get his paws dirty. Aiming a chem-powered crossbow at the gilded heart of Piltover, he has vowed to show those in the city above just how filthy they really are. Always a sneaky sneak, when he's not rooting around in the Sump, he's digging deep into other people's garbage for discarded treasures… and perhaps a moldy sandwich.

Twitch builds for Wild Rift

Build #1:

0 Items:
  • Bloodthirster
  • Phantom Dancer
  • Infinity Edge
  • Mortal Reminder
  • Runaan's Hurricane
Boots:
  • Gluttonous Greaves
  • Stasis Enchant
Runes:
  • Lethal Tempo
  • Brutal
  • Coup de Grace
  • Legend: Alacrity
  • Bone Plating
Spells:
  • Flash
  • Ghost

Build #2:

0 Items:
  • Nashor's Tooth
  • Riftmaker
  • Runaan's Hurricane
  • Rabadon's Deathcap
  • Liandry's Torment
Boots:
  • Boots of Mana
  • Stasis Enchant
Runes:
  • First Strike
  • Gathering Storm
  • Coup de Grace
  • Legend: Bloodline
  • Overgrowth
Spells:
  • Flash
  • Smite

Build #3:

0 Items:
  • Nashor's Tooth
  • Rabadon's Deathcap
  • Liandry's Torment
  • Runaan's Hurricane
  • Riftmaker
Boots:
  • Boots of Mana
  • Stasis Enchant
Runes:
  • Lethal Tempo
  • Brutal
  • Coup de Grace
  • Legend: Alacrity
  • Bone Plating
Spells:
  • Flash
  • Ghost

Build #4:

0 Items:
  • Nashor's Tooth
  • Crown of the Shattered Queen
  • Rabadon's Deathcap
  • Runaan's Hurricane
  • Riftmaker
Boots:
  • Boots of Mana
  • Stasis Enchant
Runes:
  • Conqueror
  • Gathering Storm
  • Giant Slayer
  • Legend: Alacrity
  • Eyeball Collector
Spells:
  • Flash
  • Ghost

Build #5:

0 Items:
  • Immortal Shieldbow
  • Infinity Edge
  • Runaan's Hurricane
  • The Collector
  • Guardian Angel
Boots:
  • Berserker's Greaves
  • Stasis Enchant
Runes:
  • Lethal Tempo
  • Gathering Storm
  • Giant Slayer
  • Legend: Alacrity
  • Bone Plating
Spells:
  • Flash
  • Exhaust

Build #6:

0 Items:
  • Blade of the Ruined King
  • The Collector
  • Bloodthirster
  • Runaan's Hurricane
  • Infinity Edge
Boots:
  • Berserker's Greaves
  • Stasis Enchant
Runes:
  • Lethal Tempo
  • Sudden Impact
  • Mark of the Weak
  • Eyeball Collector
  • Legend: Alacrity
Spells:
  • Flash
  • Smite

Submit a Build for Twitch!

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Items
Boot and Enchant
Spells

Twitch Abilities

Deadly Venom

Deadly Venom ability icon

Your attacks poison enemies for 5 seconds, dealing 1 - 5 + 3.5% of True Damage per second, stacking up to 5 times.

When an enemy Champion is at maximum stacks of Deadly Venom, Twitch gains 10% - 30% Attack Speed for 5 seconds.

Monsters take 30% more damage from Deadly Venom.

Ambush

Ambush ability icon
15s 40

Twitch becomes Camouflaged and gains 10% Movement Speed for 8/9/10/11 seconds, increasing to 20% when nearby enemy champions cannot see Twitch.

For 3 seconds after exiting Camouflage, Twitch's attacks will apply an additional stack of Deadly Venom. Ambush's cooldown resets when a champion infected with Deadly Venom dies.

Camouflage: Hide from enemy champions by keeping them outside Twitch's detection radius. Attacks and offensive abilities end Camouflage early.

Venom Cask

Venom Cask ability icon
12/11/10/9s 70

Throws a cask that applies 1 stack of Deadly Venom and causes 30/35/40/45% + 6% Slow to enemies for 3 seconds. The casting time decreases with Twitch's Attack Speed.

Contaminate

Contaminate ability icon
16/15/14/13s 50/60/70/80

Deals Physical Damage to all enemies affected by Deadly Venom. Each stack deals 20/25/30/35 + 37% bonus AD + 30% damage.

Enemies at maximum stacks spread the damage to nearby targets and apply maximum stacks of Deadly Venom to them.

Deals 30% additional damage against monsters.

Spray and Pray

Spray and Pray ability icon
80/70/60s 100/100/100

For 6 seconds gain 225 Attack Range and 25/40/55 additional Attack Damage. Transforms attacks into piercing bolts that hit all enemies in a line.

Subsequent targets take 10% less damage, down to a minimum of 60%.

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